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Cell and Molecular Biology
Stressed! How plants cope through dynamic responses.
One of our greatest challenges in the next 50 years will be to realize a global society that is fully sustainable. Water is the most limiting resource for plant growth and agriculture uses between 70-80% of the fresh water supply. Despite its critical importance, key questions remain regarding how plants sense, transport and efficiently use water. My research aims to understand plant-environment interactions using a holistic approach that emphasizes the importance of developmental pathways and molecular genetic me
David Parichy and Dae Seok Eom on macrophages in Science
High numerical aperture cryogenic localization microscopy: a technique for increased precision of super-resolution reconstructions
The precision of localization-based super-resolution microscopy techniques fundamentally relies on the point-spread function of the optical system and the number of photons one can collect. Here, we report that by using a high-numerical aperture objective lens and a custom cryogenic stage, we are able to increase photon yield by 2-3 fold over room temperature, thereby achieving more precise super-resolution reconstructions of complex subcellular structures.
Rapamycin Does Not Impede Survival or Induction of Antibody Responses to Primary and Heterosubtypic Influenza Infections in Mice.
Submitted by Justine-Liepkalns on
RIG-I ligand enhances the immunogenicity of recombinant H7HA protein.
Submitted by Justine-Liepkalns on
A highly immunogenic vaccine against A/H7N9 influenza virus.
Submitted by Justine-Liepkalns on
Prior infection with influenza virus but not vaccination leaves a long-term immunological imprint that intensifies the protective efficacy of antigenically drifted vaccine strains.
Submitted by Justine-Liepkalns on
Antigen modulation confers protection to red blood cells from antibody through Fcγ receptor ligation.
Submitted by Justine-Liepkalns on
Resistance of a subset of red blood cells to clearance by antibodies in a mouse model of incompatible transfusion.
Submitted by Justine-Liepkalns on
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