Microtubules Regulate Tissue-Level Navigation in Skin-Resident Macrophages
Immune cells rapidly respond to tissue damage through dynamic properties of the cytoskeleton. How microtubules control immune cell functions during injury responses remains poorly understood. Within skin, tissue-resident macrophages known as Langerhans cells use dynamic dendrites to surveil the epidermis for damage and migrate through a densely packed epithelium to wounds. Here, we used Langerhans cells within the adult zebrafish epidermis as a model to investigate roles of microtubules in immune cell tissue surveillance, phagocytosis and directed migration.
Biology in a social context: a comprehensive analysis of humanization in introductory biology textbooks
To grapple with the sterility and Whiteness of Western science, scholars have proposed a pedagogical shift to culturally relevant and/or culturally sustaining pedagogy. A key tenet of culturally relevant pedagogy is a focus on developing students’ ability to use the knowledge they obtain to identify, analyze, and solve real-world problems. Thus, the ability to foster this consciousness among students and make justice/injustice visible within biology curricula is an act of humanization.