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Cell and Molecular Biology
Kelly Hennessey PhD Defense
Identification and Validation of Small- Gatekeeper Kinases as Drug Targets in Giardia lamblia
Submitted by Kelly-Hennessey on
Sonia Singhal PhD Defense
Molecular evolution of Drosophila Cdc6, an essential DNA replication-licensing gene, suggests an adaptive choice of replication origins
Submitted by Ben-Wiggins on
Alumna Yasmeen Hussain receives AAAS Congressional Fellowship
2017 Mindlin Lecture
Stressed! How plants cope through dynamic responses.
One of our greatest challenges in the next 50 years will be to realize a global society that is fully sustainable. Water is the most limiting resource for plant growth and agriculture uses between 70-80% of the fresh water supply. Despite its critical importance, key questions remain regarding how plants sense, transport and efficiently use water. My research aims to understand plant-environment interactions using a holistic approach that emphasizes the importance of developmental pathways and molecular genetic me
David Parichy and Dae Seok Eom on macrophages in Science
High numerical aperture cryogenic localization microscopy: a technique for increased precision of super-resolution reconstructions
The precision of localization-based super-resolution microscopy techniques fundamentally relies on the point-spread function of the optical system and the number of photons one can collect. Here, we report that by using a high-numerical aperture objective lens and a custom cryogenic stage, we are able to increase photon yield by 2-3 fold over room temperature, thereby achieving more precise super-resolution reconstructions of complex subcellular structures.