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Cell and Molecular Biology
Prof. Emeritus Jim Truman elected to the National Academy of Sciences for 2022
New research led by Z Yan Wang finds changes in cholesterol production leads to octopus death
HHMI Gilliam Seminar Series: Assessment of viral influence on plant root colonization by plant growth promoting rhizobacteria
Beneficial members of the plant microbiome can increase nutrient availability for their hosts, protect their hosts against pathogens, and enhance host resilience against abiotic stress. While previous and ongoing studies of the rhizosphere microbiome have been critical for assessing the impact of specific plant-microbe interactions, their focus has overwhelmingly targeted bacterial and fungal members of the microbiome. Viruses are ubiquitous, outnumbering all other biological entities on the planet, yet they are remarkably understudied in the rhizosphere.
Prof. Emeritus John Wingfield awarded 2022 Loye & Alden Miller Research Award by the American Ornithological Society
A Simple Twist of Fate: Genetic Analysis of Neural Crest Cell Fate Determination
Single cell approaches are causing biologists to re-evaluate classical ideas of cell types and how they arise during embryonic development. One population of particular interest is the neural crest, because it migrates throughout the body to give rise to a huge variety of derivatives such as peripheral neurons, pigment cells and bones of the skull. How do such migratory cells navigate through ever-changing environments yet reliably acquire these diverse fates? Our single cell transcriptomic studies in zebrafish suggest that they do so through a series of lineage bifurcations.
Modularity-driven diversification of pathogen effectors
The dynamic interplay between virulence factors of a pathogen and the immune system of a host determines whether disease will occur. A deep understanding of the molecular mechanisms that underlie host-pathogen arms race is essential for developing durable resistance. Pathogens have evolved a large and diverse complement of virulence proteins, called effectors, which, collectively, are indispensable for disease development. An important feature of effectors is their fast evolution driven by adaptation towards a host.
HHMI Gilliam Series Seminar: Identifying Demethylase Transcriptional Regulators
UW team including Tom Daniel developed tiny battery-free devices that float in the wind like dandelion seeds
Adam Steinbrenner in Nature on adapting to make hybrid academic research work
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