During development, neural stem cells (NSCs) generate diverse cell types that self-assemble to form neural circuits regulating distinct behaviors. How neural cell types are specified and assembled into neural circuits is poorly understood.

The study of cell shape has taught us many lessons about cellular function; however, we are just beginning to understand how this basic attribute drives form and function at the level of multicellular tissues. The goal of my research program is to uncover the emergent properties that cells use to generate and maintain higher-order tissue structures.

Many eukaryotes, pathogenic and free-living alike, encyst during their life cycle. How these various organisms sense their environment to determine when and where to differentiate is largely unknown. Our recent work on the intestinal parasite Giardia lamblia has demonstrated that intestinal bile and elevated pH deplete cholesterol rich lipid rafts from the parasite plasma membrane which upregulates cyclic adenosine monophosphate (cAMP) production and initiates encystation. I will present our recent work on the regulation of encystation in Giardia.

By sharing my experiences and perspectives as a teaching professor, I hope to contribute to the ongoing demystification of the diverse pathways taken by teaching professors as they contribute to our shared missions of teaching, service, and scholarship. During this interactive presentation, we will have opportunities to reflect on and discuss strategies for building community, engaging learners, and improving equity, both in the classroom and beyond the classroom.