Mechanics of anteroposterior axis formation in vertebrates
Measuring cell-generated forces and tissue mechanical properties in vivo and in situ has proven very difficult. For this reason, our understanding of how feedback loops between biochemical signaling and mechanics contribute to robust multicellular morphogenesis is still poor. To address this limitation, I helped develop a technique based on ferrofluid droplets which allows to measure multiple mechanical parameters at time- and length-scales relevant for embryonic development.
