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Development

Environmental control of somatosensory neuron development and function

My laboratory’s long-term goal is to understand how environmental signals shape somatosensory neuron (SSN) structure and function. SSNs shape our experience of the world, allowing for perception and discrimination of pain, touch, pressure, and movement, and are a focal point of a growing human health crisis. Nearly twenty million Americans suffer from peripheral neuropathies, and one in three individuals in the U.S. will suffer from chronic pain.

A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

Jiang N, Rasmussen JP, Clanton JA, Rosenberg MF, Luedke KP, Cronan MR, Parker ED, Kim H-J, Vaughan JC, Sagasti A et al..  2019.  A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites. Elife. 8

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