Up close and personal: Short-range heat and humidity detectors for mosquito host-seeking and egg-laying behaviors
Mosquitoes use multiple host-associated cues to efficiently locate sources of blood. While detection mechanisms for longer-range cues like CO2 and odors have been widely studied, less is known about how mosquitoes sense the short-range heat and humidity gradients surrounding hosts. We recently demonstrated that heat-seeking in the malaria vector Anopheles gambiae is driven by cooling-activated neurons requiring the Ionotropic Receptor (IR) subunit IR21a.