Computational modeling of emergent spatiotemporal cell population dynamics: A survey of our successes, challenges, and best practices.
Computational models are essential tools that can be used to simultaneously explain and guide biological intuition. My lab employs agent-based modeling, machine learning, and dynamical systems to explain biological observations and to uncover design principles that drive individual cellular decisions as well as cell population dynamics. We are interested in the inherent multiscale nature of biology, with a specific focus on system-level dynamics that emerge from interactions of simpler individual-level modules.