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David W. Raible
My lab is interested in how cells acquire their distinct characteristics as development proceeds. We study cell fate determination in two sets of developmental structures: the neural crest and ectodermal placodes. Neural crest cells delaminate from the neural tube to migrate away and form neurons and glia of the peripheral nervous system, pigment cells and craniofacial cartilages. Ectodermal placodes form as distinct thickenings in the nonneural ectoderm from which peripheral neurons and sensory structures are derived. We use the genetics and embryology of the zebrafish to identify molecular regulators of these processes. We are also interested in how peripheral nervous system structures respond to damage and regenerate. We study how lateral line mechanosensory hair cells die and how they regenerate.
B.A. Cornell University, 1983
Ph.D. University of Pennsylvania, 1989.
Postdoc, University of Oregon, 1990-1995