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Genetics and Genomics
Meiosis is a highly conserved eukaryotic cell division that produces gametes required for sexual reproduction. During meiosis, homologous chromosomes undergo recombination, which can result in reciprocal crossover and gene conversion. Meiosis and recombination have a profound effect on natural genetic variation and genome evolution, which in turn has strategic importance for crop breeding. I will present our work using genome-wide methods to map meiotic recombination, primarily in the model plant Arabidopsis thaliana.
Dr. Jeff Riffell
Many biological phenomena arise from the scaling from individual interactions (e.g., between genes, proteins, metabolites, cells including neurons, organs, organisms, and species) to systems. Network approaches have transformed the study of such systems, given that the structure of networks is typically non-random and often strongly related to system-level functioning and response to perturbations. Still, many network structural features are associated with clear trade-offs.