The Moens lab is broadly interested in how genes control the cell-cell interactions that underlie the development and regeneration of neural circuits in the complex 4-dimensional environment of the embryonic brain. Specifically, we seek to understand mechanisms of neural topographic map formation in the context of the vagus nerve, which is the main route of neuronal communication between the visceral organs and the brain, as well as other axon guidance events. For these studies we use the transparent zebrafish embryo, which is exquisitely accessible both to genetic manipulation and to high-resolution imaging of single neurons, their growing axons, and their activity in vivo
For current projects and publications, please visit the Moens Lab Web site: https://research.fredhutch.org/moens/en.html