CRISPR-guided insights into the physiology and evolution of methanogenic archaea
Members of the Archaea (the third domain of life) that can produce methane are referred to as methanogens. These organisms are prevalent in a wide range of anoxic environments, including the human distal gut, and account for 75 to 80 percent of the annual methane emissions on our planet. Therefore methanogens have significant implications for climate science, biotechnology and even aspects of human health. Despite their importance, the physiology and evolution of methanogens is still poorly understood.