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Behavior

Environmental control of somatosensory neuron development and function

My laboratory’s long-term goal is to understand how environmental signals shape somatosensory neuron (SSN) structure and function. SSNs shape our experience of the world, allowing for perception and discrimination of pain, touch, pressure, and movement, and are a focal point of a growing human health crisis. Nearly twenty million Americans suffer from peripheral neuropathies, and one in three individuals in the U.S. will suffer from chronic pain.

Consumer-resource interactions in the Anthropocene: oscillations, perturbations and persistence

Consumer-resource interactions play a fundamental role in all communities, be they natural or agricultural.  I will talk about how intrinsically-generated oscillations,Consumer-resource interactions play a fundamental role in all communities, be they natural or agricultural.  I will talk about how intrinsically-generated oscillations, arising from the conflict of interest between resource and consumer species influence the evolution of the functional response, and how extrinsic perturbations such as climate warming influence the dynamics and persistence of consumer-resource intera

A Day in the Life of a Cyanobacterium: integrating temporal and environmental information

Cells of diverse organisms, from cyanobacteria to humans, execute temporal programs that are driven by circadian oscillators. The circadian clock of the cyanobacterium Synechococcus elongatus is a discrete nanomachine comprising three proteins – KaiA, KaiB, and KaiC – which interact progressively to set up the timekeeping mechanism, and two kinases whose activities are altered by engaging the Kai oscillator.

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