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Developmental expression of Drosophila Wiskott-Aldrich Syndrome family proteins.

TitleDevelopmental expression of Drosophila Wiskott-Aldrich Syndrome family proteins.
Publication TypeJournal Article
Year of Publication2012
AuthorsRodriguez-Mesa E, Abreu-Blanco M T, Rosales-Nieves AE, Parkhurst SM
JournalDevelopmental dynamics : an official publication of the American Association of Anatomists
Volume241
Issue3
Pagination608-26
Date Published2012 Mar
ISSN1097-0177
KeywordsAnimals, Antibodies, Monoclonal, Drosophila melanogaster, Drosophila Proteins, Neurons, Microfilament Proteins, Oogenesis, Vesicular Transport Proteins, Wiskott-Aldrich Syndrome, Wiskott-Aldrich Syndrome Protein
Abstract

<p>Wiskott-Aldrich Syndrome (WASP) family proteins participate in many cellular processes involving rearrangements of the actin cytoskeleton. To the date, four WASP subfamily members have been described in Drosophila: Wash, WASp, SCAR, and Whamy. Wash, WASp, and SCAR are essential during early Drosophila development where they function in orchestrating cytoplasmic events including membrane-cytoskeleton interactions. A mutant for Whamy has not yet been reported.</p>

DOI10.1002/dvdy.23742
Alternate JournalDev. Dyn.