Modularity-driven diversification of pathogen effectors
The dynamic interplay between virulence factors of a pathogen and the immune system of a host determines whether disease will occur. A deep understanding of the molecular mechanisms that underlie host-pathogen arms race is essential for developing durable resistance. Pathogens have evolved a large and diverse complement of virulence proteins, called effectors, which, collectively, are indispensable for disease development. An important feature of effectors is their fast evolution driven by adaptation towards a host.