Submitted by Clemens-Cabernard on
| Title | Neurogenesis: premature mitotic entry lets cleavage planes take off! |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Singh P, Cabernard C |
| Journal | Current biology : CB |
| Volume | 22 |
| Issue | 1 |
| Pagination | R25-8 |
| Date Published | 2012 Jan 10 |
| ISSN | 1879-0445 |
| Keywords | cdc25 Phosphatases, Humans, Microcephaly, Mitosis, Nerve Tissue Proteins, Neurogenesis, Protein Kinases |
| Abstract | <p>Mutations in the gene microcephalin/MCPH1 result in the neurodevelopmental disease microcephaly. A recent report provides evidence that MCPH1 controls neuroprogenitor entry into mitosis via the Chk1-Cdc25b centrosome maturation pathway.</p> |
| DOI | 10.1016/j.cub.2011.11.015 |
| Alternate Journal | Curr. Biol. |