You are here

Postembryonic neuronal addition in zebrafish dorsal root ganglia is regulated by Notch signaling.

TitlePostembryonic neuronal addition in zebrafish dorsal root ganglia is regulated by Notch signaling.
Publication TypeJournal Article
Year of Publication2012
AuthorsMcGraw H F, Snelson CD, Prendergast A, Suli A, Raible DW
JournalNeural development
Volume7
Pagination23
Date Published2012
ISSN1749-8104
KeywordsAnimals, Animals, Genetically Modified, Homeodomain Proteins, Ganglia, Spinal, Gene Expression Regulation, Developmental, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Nerve Tissue Proteins, Quantitative Trait Loci, Neurogenesis, Neurons, Receptor, Notch1, Signal Transduction, Zebrafish, Zebrafish Proteins
Abstract

<p>The sensory neurons and glia of the dorsal root ganglia (DRG) arise from neural crest cells in the developing vertebrate embryo. In mouse and chick, DRG formation is completed during embryogenesis. In contrast, zebrafish continue to add neurons and glia to the DRG into adulthood, long after neural crest migration is complete. The molecular and cellular regulation of late DRG growth in the zebrafish remains to be characterized.</p>

DOI10.1186/1749-8104-7-23
Alternate JournalNeural Dev