de la Iglesia,Horacio

Professor
horaciod@u.washington.edu
206-616-4697 (office)
206-616-3932 (lab)
Web site
KIN 146

Research Overview

Research in our laboratory is guided to understand the neural basis of behavior. Specifically, we are interested in biological timing, which can be studied at different levels of organization, using different approaches and throughout the phylogenetic tree.

Virtually all living species have biological clocks that generate and control the daily cyclic variations in physiology and behavior, such us rhythms in locomotor activity, temperature and hormonal secretion. In mammals, the master control of these so-called circadian rhythms is exerted by a biological clock located within the suprachiasmatic nucleus (SCN) of the brain. We use behavioral, physiological and molecular techniques in order to understand how the SCN generates and orchestrates this array of circadian rhythms.

Species of the intertidal zone show also behavioral and physiological rhythms synchronized to the tidal cycle. These circatidal rhythms also rely on biological clocks and a second line of research in our laboratory is directed to identify the molecular mechanisms and neural pathways by which these clocks are able to sustain rhythms in decapod crustaceans.


Biography

Horacio de la Iglesia finished his undergraduate studies in Biology at the University of Buenos Aires, Argentina. He got his PhD in Neuroscience and Behavior at the University of Massachusetts, Amherst, where working with Eric Bittman he studied the neuroanatomical interactions between the master circadian clock of mammals and the brain centers that control reproduction . He then continued his research on the neural control of circadian rhythms as a Post-doctoral Fellow and as an Instructor in the laboratory of William Schwartz at the University of Massachusetts Medical School. He was also an Instructor at Harvard University where he taught a course on Stem Cells. Dr. de la Iglesia joined the University of Washington Department of Biology in 2003.


Selected Publications

de la Iglesia H , Johnson C . Biological Clocks: Riding the Tides. Current Biology. 2013;23(20):R921-R923.
Smarr BL, Schwartz MD, Wotus C, de la Iglesia HO. Re-examining "Temporal Niche". Integrative and Comparative Biology. 2013;53(1):165-74.
Kronfeld-Schor N, Dominoni D, de la Iglesia H, Levy O, Herzog ED, Dayan T, et al. Chronobiology by moonlight. Proceedings of the Royal Society B: Biological Sciences. 2013;280(1765).
Hut RA, Kronfeld-Schor N, van der Vinne V, De la Iglesia H. In search of a temporal niche. In: The Neurobiology of Circadian Timing. Vol 199. Elsevier; 2012. p. 281-304. (Progress in Brain Research; vol 199).