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Cell and Molecular Biology

Genomic regions responsible for seminal and crown root lengths identified by 2D & 3D root system image analysis

Uga Y, Assaranurak I, Kitomi Y, Larson BG, Craft EJ, Shaff JE, McCouch SR, Kochian LV.  2018.  Genomic regions responsible for seminal and crown root lengths identified by 2D & 3D root system image analysis. 19122112401655466621243886616645909294112103104427613410912511317212157863643611015658153166254

Epistasis × environment interactions among Arabidopsis thaliana glucosinolate genes impact complex traits and fitness in the field

Kerwin RE, Feusier J, Muok A, Lin C, Larson B, Copeland D, Corwin JA, Rubin MJ, Francisco M, Li B et al..  2017.  Epistasis × environment interactions among Arabidopsis thaliana glucosinolate genes impact complex traits and fitness in the field. New Phytologist. (3):1249-1263.

The cell biology and mechanics of asymmetric cell division

The human body contains ~ 3.72 x 1013 cells and 200 different cell types. Generating the right number and types of cells is vital for embryogenesis, morphogenesis and tissue homeostasis. Such cellular diversity can be generated and maintained through asymmetric cell division (ACD), an evolutionary conserved process. ACD can be manifested in sibling cell size differences, distinct biochemical and molecular identities, or differences in subsequent division patterns.

The clash of macromolecular titans: replication-transcription conflicts in bacteria

In every growing cell, the DNA replication and transcription machineries are routinely in conflict with each other. Replication-transcription conflicts have various negative outcomes, including slowing of DNA replication forks, and breaks in the DNA. Survival, despite the existence of conflicts, depends on essential conflict resolution factors that all organisms harbor. In this seminar, I will highlight some of the new insights we have gained regarding the multi-faceted effects of these encounters on key parameters of cellular function.

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